Meghan Redshaw, JD
Children’s Health Defense
February 26, 2021
Despite the purported 95% effectiveness of the Pfizer-BioNTech COVID-19 vaccine, Pfizer CEO Albert Bourla announced Thursday that the vaccine maker is testing a third dose of its vaccine in anticipation of annual booster shots.
In a press release, Pfizer stated its goal was to understand the effect of a booster on immunity against COVID caused by the circulating and newly emerging SARS-CoV-2 variants and to engage in ongoing discussions with the U.S Food and Drug Administration (FDA) and European Medicines Agency regarding a clinical trial to test a modified mRNA vaccine.
Pfizer director and board member Scott Gottlieb, who also served as former FDA commissioner in charge of vaccine approval, told CNBC the vaccine maker is exploring two paths to boost effectiveness of the COVID vaccine.
The first study will give 144 participants from the phase 1 clinical trial conducted last May a third lower-dosage of the current two-dose formulation. The second study involves testing a modified version of the existing vaccine designed to provide broad defense against a range of COVIDmutations.